BDBM79181 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazino)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::MLS001146870::SMR000059133::TRIFLUOPERAZINE::TRIFLUOPERAZINE DIHYDROCHLORIDE::Trifluperazine::US11542290, Compound Trifluoperazine::cid_2913535::cid_5566

SMILES CN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1

InChI Key InChIKey=ZEWQUBUPAILYHI-UHFFFAOYSA-N

Data  71 KI  22 IC50  6 Kd

PDB links: 7 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 79181   

TargetSerotonin 2 (5-HT2) receptor(RAT)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM79181(10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoro...)
Affinity DataKi:  5.20nMAssay Description:The compound was tested for its binding affinity towards 5-hydroxytryptamine 2 receptor by displacing [3H]ketanserin radioligand in rat cerebral cort...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM79181(10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoro...)
Affinity DataKd:  1.04nMAssay Description:Compound was tested for its effect on 5-hydroxytryptamine 2 receptor saturation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed